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The Embassy of Good Science

Publications

The project’s publications will be uploaded here:

Name File Author DOI
Name of the file Sex differences in behaviour and molecular pathology in the 5XFAD model.pdf (7.9 MB) ​Annesha Sil, Arina Erfani, Nicola Lamb, Rachel Copland, Gernot Riedel, Bettina Plat DOI: 10.3233/jad-210523
Name of the file Choice of y-axis can mislead readers.pdf (305.9 KB) Betül R. Erdogan1 & Jan Vollert2 & Martin C. Michel DOI: 10.1007/S00210-020-01926-X
Name of the file The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments.pdf (1023.5 KB) Jan Vollert, Malcolm Macleod, Ulrich Dirnagl, Martien J. Kas, Martin C. Michel, Heidrun Potschka, Gernot Riedel, Kimberley E. Wever, Hanno Würbel, Thomas Steckler, EQIPD Consortium & Andrew S. C. Rice DOI: 10.1038/s41592-022-01615-y

The project’s publications:

Name Journal Author DOI
Introduction to the EQIPD quality system eLife, 2021 Bespalov, Bernard, Gilis, et al. DOI: 10.7554/eLife.63294
Sex differences in behaviour and molecular pathology in the 5XFAD model BioRXIV, 2021 ​Sil, Erfani, Lamb, Copland, Riedel, Plat DOI: 10.3233/jad-210523
Choice of y-axis can mislead readers Naunyn-Schmiedeberg’s Arch Pharmacol., 2020 Betül R. Erdogan1 & Jan Vollert2 & Martin C. Michel DOI: 10.1007/S00210-020-01926-X
Reproducibility of animal research in light of biological variation. Nat Rev Neurosci., 2020 Voelkl B, Altman NS, Forsman A et al. DOI: 10.1038/s41583-020-0313-3
Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals. BMJ Open Science, 2020 Vollert J, Schenker E, Macleod M The EQIPD WP3 study group members, et al. DOI: 10.1136/bmjos-2019-100046
Do overactive bladder symptoms and their treatment‐associated changes exhibit a normal distribution? Implications for analysis and reporting. Neurourology and Urodynamics, 2020 Amiri M, Murgas S, Stang A, Michel MC DOI: 10.1002/nau.24275
Bespalov A, Michel MC, Steckler T (eds). Good Research Practice in Non-Clinical Pharmacology and Biomedicine Handbook of Experimental Pharmacology, 2020 Bespalov A, Michel MC, Steckler T ISBN: 978-3-030-33658-5
Normalization of organ bath contraction data for tissue specimen size: does one approach fit all? Naunyn-Schmiedeberg’s Arch Pharmacol, 2020 Erdogan BR, Karaomerlioglu I, Yesilyurt ZE et al. DOI: 10.1007/s00210-019-01727
New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology Molecular Pharmacology., 2020 Michel MC, Murphy TJ and Motulsky HJ DOI: 10.1124/mol.119.118927
Be positive about negatives-recommendations for the publication of negative (or null) results Be positive about negatives-recommendations for the publication of negative (or null) results. Eur Neuropsychopharmacol 2019 Bespalov A, Steckler T, Skolnick P DOI: 10.1016/j.euroneuro.2019.10.007
Blinding and Randomization Handbook of Experimental Pharmacology, Vol. 257 Bespalov A, Wicke K, Castagné V DOI: 10.1007/164_2019_279
Quality in Non-GxP Research Environment Handbook of Experimental Pharmacology, Vol. 257 Bongiovanni S, Purdue R, Kornienko O, and Bernard R DOI: 10.1007/164_2019_274
Resolving the Tension Between Exploration and Confirmation in Preclinical Biomedical Research Handbook of Experimental Pharmacology, Vol. 257 Dirnagl U DOI: 10.1007/164_2019_278
Building Robustness into Translational Research Handbook of Experimental Pharmacology, Vol. 257 Erdogan BR, Michel MC DOI: 10.1007/164_2019_283
Electronic Lab Notebooks and Experimental Design Assistants Handbook of Experimental Pharmacology, Vol. 257 Gerlach B, Untucht C, Stefan A DOI: 10.1007/164_2019_287
Quality Governance in Biomedical Research Handbook of Experimental Pharmacology, Vol. 257 Gilis A DOI: 10.1007/164_2019_291
Good Research Practice: Lessons from Animal Care and Use Handbook of Experimental Pharmacology, Vol. 257 Guillén J and Steckler T DOI: 10.1007/164_2019_292
Name Journal Author DOI
General Principles of Preclinical Study Design Handbook of Experimental Pharmacology, Vol. 257 Huang W, Percie du Sert N, Vollert J, and Rice ASC DOI: 10.1007/164_2019_277
Guidelines and Initiatives for Good Research Practice Handbook of Experimental Pharmacology, Vol. 257 Kabitzke P, Cheng KM, and Altevogt B DOI: 10.1007/164_2019_275
Design of Meta-Analysis Studies Handbook of Experimental Pharmacology, Vol. 257 Macleod MR, Tanriver-Ayder E, Hair K, and Sena E DOI: 10.1007/164_2019_289
Minimum Information in In Vivo Research Handbook of Experimental Pharmacology, Vol. 257 Voehringer P and Nicholson JR DOI: 10.1007/164_2019_285
Learning from Principles of Evidence-Based Medicine to Optimize Nonclinical Research Practices Handbook of Experimental Pharmacology, Vol. 257 Lefevre IA and Balice-Gordon RJ DOI: 10.1007/164_2019_276
A European initiative to unclog pipeline for new medicines Nature, 2019 Macleod M, Steckler T DOI: 10.1038/d41586-019-01293-5
Synaptic dysfunction and memory impairments in transgenic Alzheimer’s disease models: A systematic review protocol OSF Storage, 2019 Hair K, Almenar JP and Sena E on behalf of the EQIPD WP2 study group DOI: 10.17605/OSF.IO/PKWH8*
The open field test protocol in transgenic Alzheimer’s disease models: A systematic review protocol Sena E and Hair K on behalf of the WP2 study group DOI: 10.17605/OSF.IO/E4WBF
Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals BMJ Open Science, 2018 Vollert J, Schenker E, Macleod M, Bespalov A, Wuerbel H, Michel MC, Dirnagl U, Potschka H, Wever KE, Steckler T, Altevogt B, Rice A DOI: 10.1136/bmjos-2018-000004
European Quality in Preclinical Data (EQIPD): een breed consortium voor het verbeteren van de kwaliteit van proefdieronderzoek Biotechniek, 2018 Steckler T, Macleod M, Kas MJ, Gilis A, Wever KE LINK
Commentary on the BJP’s new statistical reporting guidelines British Journal of Pharmacology, 2018 Motulsky HJ, Michel MC DOI: 10.1111/bph.14441